Tumescent Liposuction without Lidocaine
نویسندگان
چکیده
منابع مشابه
Tumescent Liposuction without Lidocaine
BACKGROUND Our previous study demonstrated that lidocaine has a negative impact on adipose-derived stem cell (ASC) survival. Currently for large-volume liposuction, patients often undergo general anesthesia; therefore, lidocaine subcutaneous anesthesia is nonessential. We hypothesized that removing lidocaine from tumescent might improve stromal vascular fraction (SVF) and ASC survival from the ...
متن کامل"Tumescent" liposuction alert: deaths from lidocaine cardiotoxicity.
In our just-completed survey of complications following cosmetic surgery, preliminary analysis identified a number of deaths in which lidocaine (Xylocaine) overdosage-the result of multi-liter injection of "tumescent anesthesia" solution (500-1000 mg lidocaine + 1 mg epinephrine per liter)may have played an heretofore unrecognized contributory and perhaps even causative role. Multiliter subcuta...
متن کاملTumescent Liposuction: A Review
Liposuction is a cosmetic procedure to remove fat. Liposuction may be performed either under general anaesthesia or under local anaesthesia. The procedure has been reported to be associated with significant morbidity and risk of mortality under general anaesthesia. Since the first description by Jeffrey Klein, dermatologic surgeons have made significant contributions in this field, and tumescen...
متن کاملLidocaine toxicity with tumescent liposuction. A case report of probable drug interactions.
When two or three drugs are each substrates for the same enzyme, there is a possibility for an adverse drug reaction when used simultaneously. Lidocaine is rapidly and almost exclusively eliminated by CYP3A4. The newer antidepressant selective serotonin reuptake inhibitors (SSRI) such as sertraline are metabolized by the hepatic enzymes CYP3A4 and CYP2D6. The benzodiazepines such as midazolam (...
متن کاملTumescent technique for regional anesthesia permits lidocaine doses of 35 mg/kg for liposuction.
The tumescent technique for local anesthesia permits regional local anesthesia of the skin and subcutaneous tissues by direct infiltration. The tumescent technique uses large volumes of a dilute anesthetic solution to produce swelling and firmness of targeted areas. This investigation examines the absorption pharmacokinetics of dilute solutions of lidocaine (0.1% or 0.05%) and epinephrine (1:1,...
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ژورنال
عنوان ژورنال: Plastic and Reconstructive Surgery - Global Open
سال: 2016
ISSN: 2169-7574
DOI: 10.1097/gox.0000000000000830